Interestingly, Comuzzie and collaborators (Comuzzie et al., 2012) also identified a SNP in a well-conserved paralog gene of the DBI/ACBP, referred as Acyl-CoA binding domain containing 7 (ACBD7), as associated to obesity in humans (Comuzzie et al., 2012), suggesting that ACBD7 could be involved in energy homeostasis through encoding products related to EZs. The gene discussed is ACBD7; the disease is Obesity.