LCN2 and Sepsis: For severe sepsis, plasma and urine NGAL had poor predictive values for 90-day mortality, and when combined with plasma creatinine the AUCs were 0.55 (95 % CI: 0.47 − 0.63) and 0.61 (95 % CI: 0.42 − 0.58), respectively, with optimal cutoff values of 641 and 1687 ng/ml, respectively.