Though no difference in TNMD expression was observed in insulin-resistant versus insulin-sensitive patients in subcutaneous adipose tissue depots, previous studies that analysed subcutaneous adipose tissue biopsies demonstrated a correlation of TNMD expression, fasting serum insulin levels and homeostatic model assessment-insulin resistance (HOMA-IR) in obese patients31, 33. The gene discussed is INS; the disease is Insulin resistance.