INS and gestational diabetes: GDM women who received 1000 mg/d n-3 FA supplementation (containing 180 mg of EPA and 120 mg of DHA) for 6 weeks, starting in weeks 24–28 of gestation, showed a significant decrease in serum insulin levels and in HOMA index (homoeostasis model of assessment–IR)(24), high-sensitivity C-reactive protein (CRP) and better newborn outcome(190), compared with placebo groups.