In addition, genomic stress similar to that inducing p53 may also be the cause of p63 expression in subsets of p63+ DLBCL [54], since our data showed correlation between the WT-TP53 and TP63 mRNA levels, and both WT-p53 and p63 expression were associated with increased IRF4/MUM-1 and Ki-67 expression. This evidence concerns the gene IRF4 and diffuse large B-cell lymphoma.