Nonetheless, a p53-like tumor suppressor role of p63 was suggested by the p63 GEP signatures, including downregulation of CCND2 (in WT-TP53/p63+ ABC-DLBCL), CDC27 and MYCT1 (in WT-TP53/p63+ GCB-DLBCL), CDC2L5/CDK13 and CXCR4 (in MUT-TP53/p63+ DLBCL. Here, CXCR4 is linked to diffuse large B-cell lymphoma.