The mean number of p63 positive tumor cells in the training set was 18%, which was significantly higher than that of WT-p53 (P=0.017) but significantly lower than that of mutated p53 (MUT-p53, P<0.0001, Fig 1E) (Supplemental Fig 1A, B) [37, 38], although the TP63 mRNA levels were significantly lower than the TP53 mRNA levels (P<0.0001, Fig 1F). This evidence concerns the gene TP53 and neoplasm.