CXCR2 and cancer: Cytokine/receptor genes IL17RC, IL4, IL4I1 and IL8RB/CXCR2 which have been associated with poorer prognosis in cancers, were upregulated in MUT-TP53/p63+ compared with MUT-TP53/p63− DLBCL (Supplemental Table S2); MLL2 was upregulated in p63+ patients with ABC-DLBCL and MUT-TP53 (Supplemental Fig S3D).