The state of ketosis, induced by low insulin levels, may generally benefit cancer patients, as KBs have been shown to inhibit glycolysis in various tumor cell lines73, 74 and probably also patients,75, 76, 77 and tumor cells often lack the enzymes78, 79, 80, 81 or oxygenation82 to effectively use ketones for energy production. The gene discussed is INS; the disease is cancer.