The effect of diazoxide on cancer growth was examined in DMBA- and N-methyl-N-nitrosurea (MNU)-induced mammary carcinomas of the rat.200, 201 The determination of glucose and insulin levels in the blood of DMBA-induced tumor-bearing animals showed that tumor induction itself led to significantly higher glucose and lower insulin levels than in control animals. Here, INS is linked to breast carcinoma.