In the studies that proofed tumor growth inhibition by a KD fed ad libitum, there was a significant increase in KB levels, but not necessarily decreases in blood glucose levels or body weight.74, 140, 143, 144, 145, 146, 147, 148 In some models, also non-ketogenic low-CHO diets (10–15E% CHO) led to significant tumor growth retardation that was correlated to low blood glucose and insulin levels.149, 150. The gene discussed is INS; the disease is neoplasm.