More recently query of the ONCOMINE database for PRH expression in tumour samples showed that significantly lower PRH mRNA expression occurs in activated B-cell-like diffuse large B-cell lymphoma, diffuse large B-cell lymphoma, lung adenocarcinoma, thyroid gland papillary carcinoma, superficial bladder cancer and pancreatic carcinoma [76]. The gene discussed is HHEX; the disease is lung adenocarcinoma.