TIMP1 and breast carcinoma: In detail, the TIMP-1 rs4898 heterozygous CT was not associated with breast cancer risk (OR = 0.98, 95% CI = 0.81-1.18, P = 0.8063), while the homozygous CC genotype seemed to be associated with increased breast cancer risk (OR = 1.90, 95% CI = 1.55-2.33) (Table 3).