We determined that the tumor growth was significantly inhibited in mice treated with lentivirus encoding H19 shRNA (Figure 2H), compared to those treated with lentivirus encoding control shRNA, evidenced by significantly reduced weight of tumor mass (1.272 ± 0.213g vs 2.112 ± 0.273g, p < 0.01, Figure 2I and 2J). The gene discussed is H19; the disease is neoplasm.