The Arg/Arg genotype was found to be more prevalent inCC biopsies and in individuals with progression from squamous intraepithelial lesions (SIL)to CC (Storey et al. 1998, Habbous et al. 2012), but the role of TP53 genepolymorphisms on the persistence of HPV infection is still controversy (Klug et al. 2009, Koshiol et al. 2009). The gene discussed is TP53; the disease is squamous cell intraepithelial neoplasia.