To determine involvement of Prdxs in renal fibrosis, we analyzed the expression pattern of Prdxs isotypes (Prdx1, Prdx2, Prdx3, Prdx4, Prdx5, and Prdx6) in the cortex/outer stripe of outer medulla of UUO kidney. The gene discussed is PRDX6; the disease is renal fibrosis.