To determine involvement of Prdxs in renal fibrosis, we analyzed the expression pattern of Prdxs isotypes (Prdx1, Prdx2, Prdx3, Prdx4, Prdx5, and Prdx6) in the cortex/outer stripe of outer medulla of UUO kidney. Here, PRDX4 is linked to renal fibrosis.