INS and type 2 diabetes mellitus: There was an improvement in glycemic control observed, based on the rapid decline in A1C (8.4±1.6% (68±4.5 mmol/mol) and 7.7±1.2% (61±5.3 mmol/mol) at baseline and after 4 months, respectively), showing safety and good tolerance for glargine insulin added to regular insulin in type 2 diabetes patients with diabetic nephropathy 51.