BECN1 and left ventricular hypertrophy: Pan et.al had found that miR-30a induced alterations in beclin-1 gene expression and autophagy in cardiomyocytes, angiotensin II induces down-regulation of miR-30 in cardiomyocytes and circulating miR-30 may be an important marker for the diagnosis of left ventricular hypertrophy [32].