MEN1 and parathyroid gland carcinoma: While 466,950 loci were significantly hypermethylated in MEN1-parathyroid tumors (Figure 1A), only 48,162 and 27,169 loci were significantly hypermethylation in parathyroid adenomas (Figure 1B) and parathyroid carcinomas (Figure 1C) respectively, when compared to normal parathyroids.