ULBP2 and neoplasm: Thus unlike the results that blocking the NKG2D receptor dramatically dampened the lytic activity of CIK cells against all the tumor cells, with significant differences at the E:T ratios of 40:1 (P<0.001), 20:1 (P<0.001), 10:1 (P<0.01), and 5:1 (P<0.01) (with HGC27 for example), antibody-blockade of ULBP-2 could merely induced dysfunction of CIK cells against the cells, including SW480, RKO, and MGC803 that express high levels of ULBP-2, rather than HGC27.