CTBP2 and ovarian carcinoma: We have previously identified overexpression of transcriptional corepressor protein, CtBP2, in ovarian cancer and its function in regulating cell growth and chemoresponse [14, 15], and also shown that CtBP2 is an oncogene that may play a significant role in epigenetic silencing of BRCA1 function in sporadic epithelial ovarian cancer [16].