While, high membranous EPHB2 indicated longer distant recurrence-free survival, H.R. (95%CI)=0.66 (0.41-1.05), P=0.08 and longer breast cancer survival, H.R. (95%CI)=0.47 (0.28-0.80), P=0.006 (Fig. 4G, 4H). This evidence concerns the gene EPHB2 and breast cancer.