Among them, the thiazole derivative 3-methyl-cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)]hydrazone (CPTH6), has been characterized by our group as a novel Gcn5 and pCAF HAT inhibitor, able to activate the apoptotic program and to modulate the autophagic flux in a panel of tumor cell lines [11, 12]. The gene discussed is TMPRSS11D; the disease is neoplasm.