As regards 17p deletion, a strong association of gene mutation with the deletion of the remaining allele was observed: in fact, deletion of TP53 locus globally affected 10.6% of cases [4.7% (6/128) of MM, 29.2% (7/24) of pPCL and 44.4% (4/9) of sPCL patients respectively], while its prevalence reached 58% in TP53-mutated subset (P < 0.0001). The gene discussed is TP53; the disease is Miyoshi myopathy.