Interestingly, XRCC5 (Ku80), XRCC6 (Ku70) and RAD50 are members of the non-homologous end joining (NHEJ) DNA repair machinery and are recurrently mutated genes in thyroid cancer according to the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Here, XRCC6 is linked to thyroid gland carcinoma.