TJP1 and infection: An analysis of renal biopsy specimens from hantavirus-infected patients revealed that the expression and the localization of the tight junction protein ZO-1 were altered compared to renal biopsy specimens from non-infected individuals, that both tubular and glomerular cells were affected by the infection, and that the decrease in glomerular ZO-1 correlated with disease severity induced by glomerular dysfunction (Krautkrämer et al., 2011).