Polymorphism located at 3end of VDR gene BsmI (A to G), have unknown functional effects.7 Positive association between BsmI (genotype bb) polymorphisms with reduced insulin secretory capacity was reported.8 Diabetics with BB genotype of BsmI allele in VDR gene presented higher levels of C-peptide suggesting association between VDR polymorphism and diabetes.9 This evidence concerns the gene INS and diabetes mellitus.