ELN and neoplasm: Most of the matricryptins regulating angiogenesis and tumor growth are derived from collagens IV and XVIII (Monboisse et al., 2014; Walia et al., 2015), elastin (Robinet et al., 2005; Pocza et al., 2008; Heinz et al., 2010), fibronectin (Ambesi et al., 2005), laminins (Tran et al., 2008), osteopontin (Bayless and Davis, 2001; Lund et al., 2009; Yamaguchi et al., 2012), MMPs (Bello et al., 2001; Ezhilarasan et al., 2009), proteoglycans (Goyal et al., 2011), and hyaluronan (Cyphert et al., 2015; Table 1).