GRN and frontotemporal dementia: From a clinical point of view, a high phenotypic variability is associated with GRN mutations, even in the same family (Benussi et al., 2009; Momeni et al., 2010; Pietroboni et al., 2011): specifically, Momeni et al. (2010) studied a Latino family in which SCZ and FTD coexisted, suggesting a molecular link between FTD, SCZ and GRN mutations.