Combined with our algorithm analysis, IkB‐ζ encoded by ABC DLBCL‐specific gene NFKBIZ, was essential for the expression of a specific set of NF‐kB target genes (CARD11, CD79A, CD79B, and MYD88), which were essential for ABC‐DLBCL patients' poor survival 43, 44, 45, 46. This evidence concerns the gene MYD88 and diffuse large B-cell lymphoma.