It must be noted that, both in the psychiatric (this review) and in the neurological setting [see, for example, Katoh et al. (2007) for a case with antibodies against the aminoterminal region of alpha-enolase], there have been cases with autoimmune thyroiditis which resolved without undergoing corticosteroid therapy and there may have been a publication bias against steroid-non-responsive cases. This evidence concerns the gene ENO1 and autoimmune thyroid disease.