Pilomatrixoma (PTR) [MIM:132600], Medulloblastoma (MDB) [MIM:155255], Colorectal cancer (CRC) [MIM:114500], Ovarian cancer (OC) [MIM:167000], Mesothelioma, malignant (MESOM) [MIM:156240], and Mental retardation, autosomal dominant 19 (MRD19) [MIM:615075] are all caused by mutations in CTNNB1[UniProt:P35222]. The gene discussed is CTNNB1; the disease is mesothelioma.