PDGFRA and gastrointestinal stromal tumor: Gastrointestinal stromal tumors (GISTs) develop within the digestive tract and harbor functional mutations of KIT (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) and PDGFRA (platelet-derived growth factor receptor-α) that primarily drive the tumor growth and progression [1, 2].