In order to investigate the correlation between the frequency of PD-L1-expressing neutrophils and inflammatory markers, the markers of inflammation, including ESR, neutrophil count and neutrophil percentage, serous CRP, immunoglobulin and Complement were determined and analyzed for their correlation with the frequency of PD-L1-expressing neutrophils in patients with SLE. The gene discussed is CRP; the disease is systemic lupus erythematosus.