CD79A and colitis: This study also shows that IgA-low mice are more susceptible to challenges such as Dextran Sulfate Sodium (DSS)-induced colitis, and that such susceptibility can be transferred to IgA-high mice by fecal transplantation and are driven by fecal IgA differences via a mechanism involving the ability of bacteria from IgA-low mice to degrade sIgA [17].