The tumors of patients surviving less than 6 months had a significantly higher expression of HOXB4 (p = 0.0166; Fig. 1c), and likewise a Kaplan-Meier analysis of overall survival (OS) showed that high HOXB4 tumor expression was associated with a significantly shorter OS (p = 0.041; Fig. 1d). This evidence concerns the gene HOXB4 and neoplasm.