In unadjusted Spearman’s correlation (Table 2), older age (ρ = 0.232, p = 0.041), higher body mass index (BMI) (ρ = 0.291, p = 0.010), higher 10-year CHD risk estimated by FRS (ρ = 0.264, p = 0.020), positive history of clinical CVD events (ρ = 0.369, p = 0.001), lower CD4+ T-cell nadir (ρ = -0.254, p = 0.028), and current protease inhibitor (PI) use (ρ = 0.266, p = 0.019), were significantly correlated to higher 2-year CAC Agatston score progression. Here, CD4 is linked to coronary artery disorder.