PAX8 and renal carcinoma: Though a number of renal tubule targeting mouse lines have been developed, their utility in the study of renal cancer biology is limited by lack of inducibility (Ksp-cadherin Cre [1], homeobox B7 Cre [2], Aquaporin 2 Cre [3], γ-glutamyl transpeptidase Cre [4], phosphoenolpyruvate carboxykinase Cre [5] and Six homeobox 2 Cre [6]) and/or specificity (phosphoenolpyruvate carboxykinase Cre [5], and Paired box 8 rtTA [7]).