Notable in the 6 hour-treated cells, were increased alignments to the hub genes H2AFX, FANCG, and BLM encoding proteins involved in the host response to DNA damage (Fig 4): FANCG is mutated in Fanconi Anemia, an inherited disease associated with cancer predisposition (OMIM #614082), and encodes a component of the Fanconi Anemia core complex. The gene discussed is H2AX; the disease is cancer.