PTH immunoreactivity in the adjacentnormal rim was stronger than that in the corresponding tumor cells in the majority of cases(73%; 60/82), the remaining scored equal (26%; 21/82) or weaker (1%; 1/82).PTH mRNA levels were also stronger in the normal rim than those in thecorresponding tumor cells in the majority of cases (76.5%; 65/85), the rest being equallystrong (23.5%; 20/85). The gene discussed is PTH; the disease is neoplasm.