There were no obvious differences between wild-type and Rng105+/− mice in acoustic startle response/prepulse inhibition (see Supplementary Fig. S5b,c), anxiety-like behaviors (see Supplementary Fig. S6) or in the tail suspension test (see Supplementary Fig. S7c), although the Rng105+/− mice showed increased pathological limb-clasping reflexes when suspended by the tail (see Supplementary Fig. S4q), shorter latency to withdraw their paws from a hot plate (see Supplementary Fig. S5a) and shorter immobility time in the Porsolt forced swim test (see Supplementary Fig. S7a). Here, CAPRIN1 is linked to Anxiety.