On the other hand, the biomarkers of chondrosarcoma, such as CEA, EMA, pan-K, and S-100 [26–28], showed a slight positive reaction in the spindle cells of perichondral fibrous tissue (Fig. 4G–J) but an almost negative reaction in the tumor cells of osteochondroma (Fig. 4L–N). Here, MUC1 is linked to Osteochondroma.