These included segmented negative-strand RNA viruses such as lymphocytic choriomeningitis virus (LCMV), an arenavirus that carries out cap-snatching in cytoplasm33, the non-segmented negative-strand RNA virus vesicular stomatitis virus (VSV), which shares with IAV the activation of the RIG-I RNA sensor during infection34 and sensitivity to the cellular MxA protein35, as well as respiratory syncytial virus (RSV), which causes respiratory tract infections in humans36. The gene discussed is RIGI; the disease is Respiratory tract infection.