CRP and juvenile polyposis syndrome: The alpha-defensin test had improved sensitivity (100%; 95% CI, 88.4%–100.0%) among patients who were treated with antibiotics before diagnostic testing for PJI when compared with the ESR (69.0% [95% CI, 49.17%–84.72%], p = 0.001), the CRP (79.3% [95% CI, 60.3%–92.0%], p = 0.009), the fluid PMN% (79.3% [95% CI, 60.3%–92.0%], p = 0.009), and fluid culture (70.0% [95% CI, 50.6%–85.3%], p = 0.001) (Fig. 2).