For mice treated with Pen-d/n-ATF5-RP, MRI revealed significant reduction (2/5; Figure 7, Supplementary Figure 4) or un-detectability (3/5) of tumor signals at 8 days after treatment (the earliest time monitored) and full loss of detectable tumor signal within 3 weeks (n = 7/7). Here, ATF5 is linked to neoplasm.