Supernatant from NCI-N87 gastric cancer cells with depleted OR3A4 consistently displayed a strongly inhibitory effect on angiogenesis in chicken embryos, compared with the control embryos (number of tubules 1.12 ± 0.52 vs. 8.45 ± 0.98, P < 0.001; Figure 4C). This evidence concerns the gene ENSG00000290820 and gastric cancer.