Another aptamer NOX-A12 which neutralizes CXCL12 (a critical chemokine involved in the homing and retention of hematological cancer cells) [20] was found to enhance the susceptibility of hematological cancer cells to conventional therapies, and inhibited the growth and metastasis of CXCL12-derived tumors [21-24]. Here, CXCL12 is linked to hematopoietic and lymphoid cell neoplasm.