mTOR signalling is elevated following seizure in rodent models (Waltereit et al., 2006; Grabenstatter et al., 2014) and, moreover, rapamycin has potential anticonvulsive properties in the WAG/Rij rat absence seizure model (Russo et al., 2013) and in kianic acid-induced status epilepticus in rat (Macias et al., 2013). The gene discussed is MTOR; the disease is juvenile absence epilepsy.