To date, only a few lncRNAs (including MALAT1, HOTAIR, H19, MEG3, GAS5, ANRIL, and SOX2OT etc.)have been reported to be dysregulated and functionally characterized in lung cancer and most of the studies were based on microarray expression data [40, 44, 45]. Here, CDKN2B-AS1 is linked to lung cancer.