TBX1 and cancer: Given the function of Brachyury in SCs of mouse testis and its association with cancer, we wanted to confirm the expression profile of Brachyury in normal adult human tissues, including the testis, and whether it exhibited a Cancer Testis Antigen-gene (CTA-gene)-like profile; that is, expressed in only normal adult immune-privileged tissues (i.e. testis and brain) and aberrantly in cancers [21].