To determine the effect of RKIP on NPC cell radioresistance in vitro, we established CNE2-IR cell lines with stable RKIP overexpression, CNE2 cell lines with stable RKIP knockdown and their corresponding control cell lines (Figure 2A), and then cell radiosensitivity was determined. The gene discussed is PEBP1; the disease is nasopharyngeal carcinoma.