High Ly6H mRNA expression in colorectal cancer was significantly correlated with poor five-year relapse free survival (low Ly6H, n=70; high Ly6E, n=70; HR=7.6, p=0.0326, n= number of patient, HR=hazard ratio) shown by PROGgeneV2 (Table S3, Figure 3A). Here, LY6H is linked to colorectal cancer.