LY6E and colorectal cancer: High Ly6E mRNA expression in colorectal cancer was significantly correlated with poor five-year relapse free survival with restriction of age greater than 50 years (low Ly6E, n=82; high Ly6E, n=83; HR=1.70, p=0.018) or without any restriction (low Ly6E, n=93; high Ly6E, n=94; HR=1.77, p=0.0005) shown by PROGgeneV2 (Table S2, Figure 2F).