Ly6E mRNA expression was significantly higher in tumors with TP53 mutaions (n=130) than tumors with wildtype tumor (n=261) and in tumors with BRCA1 mutaions (n=31) than tumors with BRCA1 wildtype (n=128) in Ivshina [61], Gluck [50], Pawitan [115] studies. This evidence concerns the gene TP53 and neoplasm.