High Ly6E mRNA expression in lung cancer was significantly correlated with poor five-year overall survival with restriction of stage IIIa cancer (low Ly6E, n=14; high Ly6E, n=14; HR=6.82, p=0.0273) and poor five-year relapse free survival with restriction of stage IIb cancer (low Ly6E, n=22; high Ly6E, n=23; HR=1.97, p=0.029) or with restriction of stage 1b cancer (low Ly6E, n=27; high Ly6E, n=27; HR=1.7, p=0.046) shown by PROGgeneV2 (Table S2, Figure 2D). This evidence concerns the gene LY6E and cancer.