After adjustment for age, waist circumference, resistin, CRP, PAI-1, adiponectin and glycated hemoglobin levels, the association of having insulin resistance and higher levels of IL-6 (OR = 1.390, p = 0.005) and MCP-1 (OR = 1.006, p = 0.026) became stronger (Table 3, model 4). The gene discussed is RETN; the disease is Insulin resistance.