Recently, growing biological evidence has supported chronic intermittent hypoxia due to OSA activating inflammatory pathways and increasing oxidative stress, as indicated by high serum levels of C-reactive protein (CRP), interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor (TNF)-α4, 5, 6. Here, CXCL8 is linked to obstructive sleep apnea syndrome.