HTR2A and schizophrenia: Pharmacogenetic results from the proof-of-concept study identified a significant association between 16 tightly-linked, single nucleotide polymorphisms (SNPs) in the serotonin 2A receptor gene, HTR2A, the most significant of which was rs7330461, and response to treatment with pomaglumetad methionil in Caucasian patients with schizophrenia [11].